UCD38B hydrochloride
SIGMA/SML0821 - ≥98% (HPLC)
Synonym: 5’-
CAS Number: 1115177-19-9
Empirical Formula (Hill Notation): C15H16ClN7O3 · xHCl
Molecular Weight: 377.79 (free base basis)
Linear Formula: C15H16ClN7O3 · xHCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C15H16ClN7O3.ClH/c16-1 |
InChI key | SFHYWDNJBRFZKW-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | NC(NC(C(N=C1Cl)=C(N)N=C1C |
solubility | DMSO: 15 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | UCD38B is a cell permeable inhibitor of intracellular uPA (urokinase plasminogen activator) that is cytotoxic to proliferating and non-proliferating glioma cell lines. UCD38B induces caspase-independent necrosis in U87 glioma MDA231 breast cancer cells. It appears that the necrotic pathway is mediated by AIF (apoptotic inducible factor). |
Packaging: | 5, 25 mg in glass bottle |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |