SC-1
SIGMA/SML0858 - ≥98% (HPLC)
Synonym: N-
CAS Number: 1313019-65-6
Empirical Formula (Hill Notation): C21H13ClF3N3O2
Molecular Weight: 431.80
Linear Formula: C21H13ClF3N3O2
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| Quality Level | 100 ![]() |
| solubility | DMSO: 15 mg/mL, clear |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | SC-1 is a derivative of the multiple tyrosine kinase inhibitor sorafenib with no kinase-inhibition activity. SC-1 blocks STAT3 phosphorylation and activation with similar potency to sorafenib, and induces apoptosis in hepatocellular carcinoma cell lines. |
| Biochem/physiol Actions: | SC-1 is an inhibitor of STAT3 signaling pathway. |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H319 - H413 |
| Precautionary statements | P273 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |


