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Arbidol hydrochloride

SIGMA/SML0860 - ≥98% (HPLC)

Synonym: 6-Bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-1H-Indole-3-carboxylic acid ethyl ester monohydrochloride

CAS Number: 131707-23-8
Empirical Formula (Hill Notation): C22H25BrN2O3S · HCl
Molecular Weight: 513.88
Linear Formula: C22H25BrN2O3S · HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML0860-10MG 10 mg
$84.60
1/EA
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45-SML0860-50MG 50 mg
$328.00
1/EA
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This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C22H25BrN2O3S.ClH.H2O/c1-5-28-22(27)20-18(13-29-14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3;;/h6-11,26H,5,12-13H2,1-4H3;1H;1H2
InChI key PLWQHPWNKPKQJT-UHFFFAOYSA-N
Quality Level 100 
SMILES string S(Cc2[n](c3c(c(c(c(c3)Br)O)CN(C)C)c2C(=O)OCC)C)c1ccccc1.[Cl-].O.[H+]
solubility DMSO: 20 mg/mL, clear
storage condition desiccated
storage temp. −20°C
Biochem/physiol Actions: Arbidol hydrochloride (ARB) is a small monocular compound. It is used to prevent severe pneumonia and virus-associated cytokine dysregulation induced by influenza viruses (IFV). ARB also possesses some immunomodulatory properties, including the effects of interferon induction and macrophage activation.
Biochem/physiol Actions: Arbidol is a broad-spectrum antiviral that has demonstrated activity against a number of enveloped and non-enveloped viruses, and is used clinically to treat influenza. Arbidol inhibits viral entry into host cell and stimulates immune response. Arbidol inhibits fusion between the viral capsid and the cell membrane of the target cell, thus preventing viral entry.
Biochem/physiol Actions: Arbidol is an anti-influenza antiviral agent.
Packaging: 10, 50 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H315 - H319
Precautionary statements P302 + P352 - P305 + P351 + P338
Hazard Codes Xi
Risk Statements 36/38
Safety Statements 26
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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