Purmorphamine
SIGMA/SML0868 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 483367-10-8
Empirical Formula (Hill Notation): C31H32N6O2
Molecular Weight: 520.62
Linear Formula: C31H32N6O2
Product Type: Chemical
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| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| InChI | 1S/C31H32N6O2/c1-2-9-25(1 |
| InChI key | FYBHCRQFSFYWPY-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | N7(CCOCC7)c1ccc(cc1)Nc2nc |
| solubility | DMSO: 5 mg/mL, clear (warmed) |
| storage temp. | −20°C |
| Application: | Purmorphamine has been used to study the consequences of upregulation of Hedgehog signalling pathway in Tupfel long fin strain Zebrafish. |
| Biochem/physiol Actions: | Purmorphamine activates the Hedgehog (Hh) signaling pathway, directly binding to the Smoothened (Smo) receptor. |
| Biochem/physiol Actions: | Purmorphamine activates the Hedgehog (Hh) signaling pathway, directly binding to the Smoothened (Smo) receptor. In various studies, purmorphamine has been shown to induce osteoblast differentiation, generate cardiomyocytes from human embryonic stem cells, increase the neuronal differentiation of a human striatal neural stem cell line, and to differentiate human umbilical cord mesenchymal stem cells (hUCMSCs) into motoneurons. |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 51111800 |