Filastatin

SIGMA/SML0876 - ≥98% (HPLC)

Synonym: (3-Chloro-4-methylphenyl)[4-(4-nitrophenyl)-1-piperazinyl]-methanone

CAS Number: 431996-53-1
Empirical Formula (Hill Notation): C₁₈H₁₈ClN₃O₃
Molecular Weight: 359.81
Linear Formula: C₁₈H₁₈ClN₃O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0876-25MG	25 mg	$313.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C18H18ClN3O3/c1-13-2-3-14(12-17(13)19)18(23)21-10-8-20(9-11-21)15-4-6-16(7-5-15)22(24)25/h2-7,12H,8-11H2,1H3
InChI key	PNECWWUOUHGWQG-UHFFFAOYSA-N
Quality Level	100
SMILES string	Clc1c(ccc(c1)C(=O)N2CCN(CC2)c3ccc(cc3)[N+](=O)[O-])C
solubility	DMSO: 15 mg/mL, clear
storage temp.	2-8°C

Biochem/physiol Actions:	Filastatin blocks the ability of Candida albicans, and other Candida sp. to bind to polystyrene, and human A549 cell monolayers. Filastatin also blocks biofilm formation and yeast-to-hyphal morphologic transition through inhibition of the hyphal-specific promoter HWP1.
Biochem/physiol Actions:	Filastatin is an inhibitor of Candida albicans surface binding, morphology transition and biofilm formation.
Packaging:	5, 25 mg in glass bottle

Hazard Codes	Xi,N
Risk Statements	36/37/38-50/53
Safety Statements	26-60-61
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	51111800

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