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Sertaconazole nitrate

SIGMA/SML0888 - ≥98% (HPLC)

Synonym: 1-[2-[(7-Chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate

CAS Number: 99592-39-9
Empirical Formula (Hill Notation): C20H15Cl3N2OS · HNO3
Molecular Weight: 500.78
Linear Formula: C20H15Cl3N2OS · HNO3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0888-10MG 10 mg
 $45.80
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45-SML0888-50MG 50 mg
 $179.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C20H15Cl3N2OS.HNO3/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22;2-1(3)4/h1-8,11-12,19H,9-10H2;(H,2,3,4)
InChI key HAAITRDZHUANGT-UHFFFAOYSA-N
Quality Level 100 
solubility DMSO: 20 mg/mL, clear
storage temp. −20°C
Biochem/physiol Actions: Sertaconazole nitrate is an antifungal agent with anti-inflammatory and anti-itch activity. Topical administration of this drug reduces the releases of cytokines from activated T-cell enriched human lymphocytes. Sertaconazole nitrate has been used as a highly safe and effective therapeutic for treating tinea pedis interdigitalis. It is also used to treat contact hypersensitivity and irritant contact dermatitis.
Biochem/physiol Actions: Sertaconazole nitrate is an imidazole antifungal. Like other imidazole antifungals, sertaconazole blocks the synthesis of ergosterol, an essential component of the fungal cell membrane, by inhibiting the P450 enzyme 14α-demethylase that converts lanosterol to ergosterol.
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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