bpV(phen)
SIGMA/SML0889 - ≥95% V basis
Synonym: Potassium bisperoxo(1,10-
CAS Number: 42494-73-5 (anhydrous)
Empirical Formula (Hill Notation): KVO5C12H8N2 · xH2O
Molecular Weight: 350.24 (anhydrous basis)
Linear Formula: KVO5C12H8N2 · xH2O
Product Type: Chemical
assay | ≥95% V basis |
color | faintly yellow to dark yellow |
form | powder |
Quality Level | 100 |
SMILES string | O=[V]123([N]4=CC=CC5=C4C6 |
solubility | H2O: 20 mg/mL, clear |
storage condition | protect from light |
storage temp. | −20°C |
Biochem/physiol Actions: | bpV(phen) (potassium bisperoxo(bipyridine)oxov |
Biochem/physiol Actions: | bpV(phen) is an insulin receptor kinase (IRK) activator and an inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(phen) are 38 nM for PTEN compared to 343 nM for PTPβ and 920 nM for PTP-1β. bpV(phen) has anti-inflammatory effects in oxidative stress including inhibitory effects on oxidative stress-induced cardiomyocyte injury that may be partially modulated by the action of ROS on PTEN. It may also be involved in differentiation. |
Other Notes: | Light Sensitive |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H315 - H319 - H335 |
Precautionary statements | P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 36/37/39 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% V basis |
Storage Temp. | −20°C |
UNSPSC | 12352200 |