TC3.6
SIGMA/SML0910 - ≥98% (HPLC)
Synonym: 3-
CAS Number: 16081-93-9
Empirical Formula (Hill Notation): C14H10N2S2
Molecular Weight: 270.37
Linear Formula: C14H10N2S2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | light orange to dark orange |
form | powder |
Quality Level | 100 |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | TC3.6 is a PDE7 selective inhibitor (IC50 = 1.04 μM). In an Experimental Autoimmune Encephalomyelitis (EAE) murine model, TC3.6 reduced levels of IL-17, blocked infiltration of immune cells into the CNS and elevated levels of the Treg marker Foxp3. TC3.6 also enhances survival and differentiation of oligodendrocyte precursor cells. |
Features and Benefits: | This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
Packaging: | 5, 25 mg in glass bottle |
Hazard statements | H413 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 41106305 |