NSC130813
SIGMA/SML0922 - ≥98% (HPLC)
Synonym: 4-
CAS Number: 1082532-95-3
Empirical Formula (Hill Notation): C26H27ClN4O2 · 3HCl
Molecular Weight: 572.35
Linear Formula: C26H27ClN4O2 · 3HCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | yellow to orange |
form | powder |
Quality Level | 100 |
solubility | H2O: 10 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | NSC130813 blocks protein-protein interactions between XPF and ERCC1, two proteins involved in nucleotide excision repair (NER). The compound, NSC130813, blocks repair of DNA damage induced by platinum-based ctyotoxic drugs and DNA alkylating agents. NSC130813 synergistically potentiates cell death in cancer cell lines treated with cisplatin or mitomycin C. |
Other Notes: | air sensitive |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |