Synonym: 1,1′-(6,6′-Dihydroxy-5,5′-dimethoxy[1,1′-biphenyl]-3,3′-diyl)bis-ethanone; 4′,4′′′-Dihydroxy-5′,5′′′-dimethoxy-3′,3′′′-biacetophenone (8CI); Dehydrodiacetovanillone
CAS Number: 29799-22-2
Empirical Formula (Hill Notation): C18H18O6
Molecular Weight: 330.33
Linear Formula: C18H18O6
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
white to beige |
form |
powder |
Quality Level |
100 |
solubility |
DMSO: 2 mg/mL, clear (warmed) |
storage temp. |
room temp |
Biochem/physiol Actions: |
Diapocynin is a covalent dimer of apocynin, and a functional metabolite of the same. It is generated by neutrophil activation via myeloperoxidase-mediated oxidation. Studies show that diapocynin has greater neuroprotection compared to apocynin. |
Biochem/physiol Actions: |
Diapocynin, a proposed NADPH oxidase (NOX) inhibitor, is an anti-inflammatory and antioxidant agent. Diapocynin attenuates oxidative damage and neuroinflammatory responses in animal model of Parkinson’s disease. Diapocynin reverses deficient motor coordination in LRRK2R1441Gtg mice of PD. |
Packaging: |
5, 25 mg in glass bottle |
Symbol |
GHS09 |
Signal word |
Warning |
Hazard statements |
H410 |
Precautionary statements |
P273 - P501 |
Hazard Codes |
N |
Risk Statements |
50/53 |
Safety Statements |
60-61 |
RIDADR |
UN 3077 9 / PGIII |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
room temp |
UNSPSC |
12352200 |