Synonym: TMC-114; UIC-94017; [(1R,5S,6R)-2,8-dioxabicyclo[3.3.0]oct-6-yl] N-[(2S,3R)-4- [(4-aminophenyl)sulfonyl- (2-methylpropyl)amino]-3-hydroxy-1-phenyl- butan-2-yl]
CAS Number: 206361-99-1
Empirical Formula (Hill Notation): C27H37N3O7S
Molecular Weight: 547.66
MDL Number: MFCD09260006
Linear Formula: C27H37N3O7S
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
white to beige |
form |
powder |
InChI |
1S/C27H37N3O7S/c1-18(2)15-30(38(33,34)21-10-8-20(28)9-11-21)16-24(31)23(14-19-6-4-3-5-7-19)29-27(32)37-25-17-36-26-22(25)12-13-35-26/h3-11,18,22-26,31H,12-17,28H2,1-2H3,(H,29,32)/t22-,23-,24+,25-,26+/m0/s1 |
InChI key |
CJBJHOAVZSMMDJ-HEXNFIEUSA-N |
Quality Level |
100 |
shipped in |
wet ice |
SMILES string |
[H][C@]1([C@@H](OC(N[C@@H](CC2=CC=CC=C2)[C@@H](CN(S(C3=CC=C(N)C=C3)(=O)=O)CC(C)C)O)=O)CO4)[C@]4([H])OCC1 |
solubility |
DMSO: 20 mg/mL, clear |
storage condition |
desiccated |
storage temp. |
−20°C |
Biochem/physiol Actions: |
Darunavir has been sanctioned by the food and drug administration (FDA) as the first treatment of drug-resistant human immunodeficiency virus (HIV). |
Biochem/physiol Actions: |
Darunavir is a second-generation antiviral HIV protease inhibitor with broad spectrum activity. |
Packaging: |
10, 50 mg in glass bottle |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
−20°C |
UNSPSC |
12352200 |