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NK-252

SIGMA/SML0944 - ≥98% (HPLC)

Synonym: N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N′-(2-pyridinylmethyl)-urea

CAS Number: 1414963-82-8
Empirical Formula (Hill Notation): C13H11N5O3
Molecular Weight: 285.26
Linear Formula: C13H11N5O3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0944-5MG 5 mg
 $63.30
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45-SML0944-25MG 25 mg
 $249.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C13H11N5O3/c19-12(15-8-9-4-1-2-6-14-9)16-13-18-17-11(21-13)10-5-3-7-20-10/h1-7H,8H2,(H2,15,16,18,19)
InChI key FNSCFQXZZNCDAI-UHFFFAOYSA-N
Quality Level 100 
SMILES string N(Cc3ncccc3)C(=O)Nc1nnc([o]1)c2[o]ccc2
solubility DMSO: 20 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: NK-252 is a very potent, specific activator of the transcription factor Nrf2, which activates antioxidant-associated genes. NK-252 induces expression of an antioxidant response element promoter driven reporter gene, and protects Huh-7 liver cells against H202 induced cytotoxicity.
Biochem/physiol Actions: NK-252 is a very potent, specific activator of the transcription factor Nrf2.
Features and Benefits: This compound is a featured product for Gene Regulation research. Click here  to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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