Cirsiliol

SIGMA/SML0953 - ≥90% (HPLC)

Synonym: 2-(3,4-Dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one; 3′,4′,5-Trihydroxy-6,7-dimethoxy-flavone; 5,3′,4′-Trihydroxy-6,7-dimethoxyflavone; 6,7-Dimethoxy-5,3′,4′-trihydroxyflavone; 6-Hydroxyluteolin-6,7-dimethyl ether; 6-Methoxyluteolin 7-methyl ether; Crisiliol

CAS Number: 34334-69-5
Empirical Formula (Hill Notation): C₁₇H₁₄O₇
Molecular Weight: 330.29
Linear Formula: C₁₇H₁₄O₇
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0953-5MG	5 mg	$111.00 1/EA	Add To Favorites
45-SML0953-25MG	25 mg	$447.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥90% (HPLC)
color	white to beige
form	powder
InChI	1S/C17H14O7/c1-22-14-7-13-15(16(21)17(14)23-2)11(20)6-12(24-13)8-3-4-9(18)10(19)5-8/h3-7,18-19,21H,1-2H3
InChI key	IMEYGBIXGJLUIS-UHFFFAOYSA-N
Quality Level	100
SMILES string	[o]1c2c([c](cc1c3cc(c(cc3)O)O)=O)c(c(c(c2)OC)OC)O
solubility	DMSO: 10 mg/mL, clear
storage condition	protect from light
storage temp.	2-8°C

Biochem/physiol Actions:	Cirsiliol is a flavonoid that displays anti-inflammatory, anti-oxidant, anti-proliferative, and anti-bacterial activities.
Biochem/physiol Actions:	Cirsiliol is a flavonoid that displays anti-inflammatory, anti-oxidant, anti-proliferative, and anti-bacterial activities. Cirsiliol sensitizes non-small cell lung cancer cell lines (NSCLC) to radiation therapy. Cirsiliol inhibits epithelial-mesenchymal transition likely by induction of tumor-suppressive miR-34a, which suppresses Notch-1 expression NSCLC.
Features and Benefits:	This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Hazard Codes	Xn
Risk Statements	22
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥90% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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