Synonym: 2-(3,4-Dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one; 3′,4′,5-Trihydroxy-6,7-dimethoxy-flavone; 5,3′,4′-Trihydroxy-6,7-dimethoxyflavone; 6,7-Dimethoxy-5,3′,4′-trihydroxyflavone; 6-Hydroxyluteolin-6,7-dimethyl ether; 6-Methoxyluteolin 7-methyl ether; Crisiliol
CAS Number: 34334-69-5
Empirical Formula (Hill Notation): C17H14O7
Molecular Weight: 330.29
Linear Formula: C17H14O7
Product Type: Chemical
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| assay |
≥90% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C17H14O7/c1-22-14-7-13-15(16(21)17(14)23-2)11(20)6-12(24-13)8-3-4-9(18)10(19)5-8/h3-7,18-19,21H,1-2H3 |
| InChI key |
IMEYGBIXGJLUIS-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
[o]1c2c([c](cc1c3cc(c(cc3)O)O)=O)c(c(c(c2)OC)OC)O |
| solubility |
DMSO: 10 mg/mL, clear |
| storage condition |
protect from light |
| storage temp. |
2-8°C |
| Biochem/physiol Actions: |
Cirsiliol is a flavonoid that displays anti-inflammatory, anti-oxidant, anti-proliferative, and anti-bacterial activities. |
| Biochem/physiol Actions: |
Cirsiliol is a flavonoid that displays anti-inflammatory, anti-oxidant, anti-proliferative, and anti-bacterial activities. Cirsiliol sensitizes non-small cell lung cancer cell lines (NSCLC) to radiation therapy. Cirsiliol inhibits epithelial-mesenchymal transition likely by induction of tumor-suppressive miR-34a, which suppresses Notch-1 expression NSCLC. |
| Features and Benefits: |
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Packaging: |
5, 25 mg in glass bottle |
| Symbol |
GHS07 |
| Signal word |
Warning |
| Hazard statements |
H302 |
| Hazard Codes |
Xn |
| Risk Statements |
22 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥90% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |