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Astaxanthin

SIGMA/SML0982 - ≥97% (HPLC)

Synonym: (3S,3′S)-3,3′-dihydroxy-β,β-Carotene-4,4′-dione; trans-Astaxanthin

CAS Number: 472-61-7
Empirical Formula (Hill Notation): C40H52O4
Molecular Weight: 596.84
Linear Formula: C40H52O4
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML0982-50MG 50 mg
$136.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: SML0982-50MG

 

assay ≥97% (HPLC)
color , pink to very dark purple
form powder
InChI 1S/C40H52O4/c1-27(17-13-19-29(3)21-23-33-31(5)37(43)35(41)25-39(33,7)8)15-11-12-16-28(2)18-14-20-30(4)22-24-34-32(6)38(44)36(42)26-40(34,9)10/h11-24,35-36,41-42H,25-26H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,27-15+,28-16+,29-19+,30-20+/t35-,36-/m0/s1
InChI key MQZIGYBFDRPAKN-UWFIBFSHSA-N
Quality Level 100 
SMILES string O[C@H]1CC(C(=C(C1=O)C)C=CC(=CC=CC(=CC=CC=C(/C)C=CC=C(/C)C=CC2=C(C(=O)[C@H](CC2(C)C)O)C)C)C)(C)C
solubility DMSO: 1 mg/mL (warmed)
storage condition desiccated
  protect from light
storage temp. −20°C
Application: Astaxanthin has been used:
• as an antioxidant to study its effect on Brachionus manjavacas (Rotifera) population growth
• to study its effects on the treatment of diabetic retinopathy.
• to investigate its role in restoring the expression of Nrf2 (nuclear factor erythroid 2 p45-related factor 2) and glutathione S-transferase P1 (GSTP1) through epigenetic modification in human prostate LNCaP cells.
Biochem/physiol Actions: In vivo and in vitro studies propose that astaxanthin (AST) possesses health-promoting activities, signifying its potential use in the prevention of various diseases, such as cancers and Parkinson’s disease. Due to its bright red colour, AST has been used as a food colorant in animal feeds.
Biochem/physiol Actions: Astaxanthin is a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity.
Biochem/physiol Actions: Astaxanthin is a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity. Astaxanthin protects against oxidative stress, inhibiting NF-KB, suppressing pro-inflammatory genes and suppressing production of pro-inflammatory compounds nitric oxide, prostaglandin E2, TNF-α, and interleukin-1β. Astaxanthin′s protection of cells from oxidative stress generated by TNF-α and palmitate has been shown to ameliorate insulin resistance. Astaxanthin has also been shown to be an inhibitor of PPARγ.
General description: Astaxanthin (AST) is a red dietary carotenoid. It is mainly found in aquatic animals and microalgae, such as Haematococcus pluvialis and Chlorella zofingiensis.
Other Notes: Light and air sensitive
Packaging: 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥97% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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