Synonym: (2,3-Propandiyl-bis(2,3-dichloro)maleimide; 1,1′-(2,2-Dimethyl-1,3-propanediyl)bis[3,4-dichloro-1H-Pyrrole-2,5-dione; NSC-617145; SID 487795
CAS Number: 203115-63-3
Empirical Formula (Hill Notation): C13H10Cl4N2O4
Molecular Weight: 400.04
Linear Formula: C13H10Cl4N2O4
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
white to light brown |
form |
powder |
Quality Level |
100 |
solubility |
DMSO: 3 mg/mL, clear (warmed) |
storage temp. |
2-8°C |
Biochem/physiol Actions: |
NSC 617145 has an IC50 value of 230nM. |
Biochem/physiol Actions: |
NSC 617145 is a potent and cell-permeable inhibitor of Werner syndrome helicase (WRN) that causes accumulation of double-strand breaks (DSB) and chromosomal abnormalities in cancer cells. |
Features and Benefits: |
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
Purity |
≥98% (HPLC) |
Storage Temp. |
2-8°C |
UNSPSC |
12352200 |