L-742001 hydrochloride
SIGMA/SML1010 - ≥98% (HPLC)
Synonym: (Z)
CAS Number: 174605-64-2
Empirical Formula (Hill Notation): C23H24ClNO4 · HCl
Molecular Weight: 450.35
MDL Number: MFCD22587878
Linear Formula: C23H24ClNO4 · HCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C23H24ClNO4.ClH/c24-19 |
InChI key | LMLNSXCRZNNZBT-VSOKSMTPSA |
Quality Level | 100 |
SMILES string | O/C(C(O)=O)=CC(C(CC1)(CC |
solubility | DMSO: 20 mg/mL, clear |
storage condition | desiccated |
storage temp. | 2-8°C |
Biochem/physiol Actions: | L-742,001 is an inhibitor of the influenza virus RNA polymerase PA subunit, implicated in several roles, including endonuclease and protease activities as well as viral RNA/complementary RNA promoter binding. L-742,001 inhibits the influenza endonuclease-dependent polymerase activity with an IC50 of 430 nM. |
Biochem/physiol Actions: | L-742001 is useful in the treatment of influenza viral infection. |
Symbol | GHS07,GHS09 |
Signal word | Warning |
Hazard statements | H302 - H410 |
Precautionary statements | P273 - P301 + P312 + P330 |
Hazard Codes | Xn,N |
Risk Statements | 22-50/53 |
Safety Statements | 46-60-61 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |