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INDY

SIGMA/SML1011 - ≥98% (HPLC)

Synonym: (1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone

CAS Number: 1169755-45-6
Empirical Formula (Hill Notation): C12H13NO2S
Molecular Weight: 235.30
Linear Formula: C12H13NO2S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1011-5MG 5 mg
 $106.00
1/EA		 Add To Favorites
45-SML1011-25MG 25 mg
 $343.00
1/EA		 Add To Favorites
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C12H13NO2S/c1-3-13-10-7-9(15)4-5-11(10)16-12(13)6-8(2)14/h4-7,15H,3H2,1-2H3/b12-6+
InChI key GCSZJMUFYOAHFY-WUXMJOGZSA-N
Quality Level 100 
SMILES string S1c2c(cc(cc2)O)N(C1=C/C(=O)C)CC
solubility DMSO: 5 mg/mL, clear (warmed)
storage temp. −20°C
Biochem/physiol Actions: INDY is a potent inhibitor of Dyrk1A and Dyrk1B (dual-specificity tyrosine-phosphorylation-regulated kinase 1). The IC50 values for inhibition of Dyrk1A and 1B are 240 and 230 nM, respectively. INDY impairs the self-renewal capacity of neural stem cells and glioblastoma tumor-initiating cells.
Biochem/physiol Actions: INDY is a potent inhibitor of Dyrk1A and Dyrk1B.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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