PRT4165
SIGMA/SML1013 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 31083-55-3
Empirical Formula (Hill Notation): C15H9NO2
Molecular Weight: 235.24
MDL Number: MFCD00435709
Linear Formula: C15H9NO2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C15H9NO2/c17-14-11-5-1 |
InChI key | OMHZFEWYVFWVLI-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | O=C1C(C(C2=C1C=CC=C2)=O)= |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | PRT4165 is a potent inhibitor of PRC1 (polycomb-repressive complex 1)-mediated histone H2A ubiquitylation in vivo and in vitro. PRT4165 inhibits the in vitro histone H2A E3 ubiquitin ligase activity of PRC1 components RING1, RNF2, and a BMI1/RNF2 complex. PRT4165 also inhibits DNA double-strand breaks induced ubiquitylation of histone H2AX. |
Features and Benefits: | This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |