MPT0B014
SIGMA/SML1028 - ≥98% (HPLC)
Synonym: 6-
CAS Number: 1215208-59-5
Empirical Formula (Hill Notation): C19H17NO4
Molecular Weight: 323.34
Linear Formula: C19H17NO4
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| Quality Level | 100  |
| solubility | DMSO: 5 mg/mL, clear (warmed) |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | MPT0B014 inhibits tubulin polymerization and disrupts microtubules in the cytoskeleton. The compound MPT0B014 inhibits proliferation of the lung cancer cells A549, H1299, and H226 with IC50 values of 41, 46 and 42 nM, respectively. MPT0B014 induces cell cycle arrest and apoptosis, inhibits tumor growth in lung cancer xenografts, and potentiates inhibition of tumor growth by erlotinib. |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |