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DC260126

SIGMA/SML1050 - ≥98% (HPLC)

Synonym: N-(4-Butylphenyl)-4-fluoro-benzenesulfonamide

CAS Number: 346692-04-4
Empirical Formula (Hill Notation): C16H18FNO2S
Molecular Weight: 307.38
Linear Formula: C16H18FNO2S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1050-5MG 5 mg
 $94.80
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C16H18FNO2S/c1-2-3-4-13-5-9-15(10-6-13)18-21(19,20)16-11-7-14(17)8-12-16/h5-12,18H,2-4H2,1H3
InChI key CNGHPXKWPGIDSK-UHFFFAOYSA-N
Quality Level 100 
SMILES string Fc1ccc(cc1)[S](=O)(=O)Nc2ccc(cc2)CCCC
solubility DMSO: 20 mg/mL, clear
storage condition desiccated
storage temp. −20°C
Biochem/physiol Actions: DC260126 is a FFA1 (GPR40) selective antagonist.
Biochem/physiol Actions: DC260126 is a FFA1 (GPR40) selective antagonist. In FFA1-expressing CHO cells, DC260126 blocks linoleic acid-induced Ca2+ elevation and ERK phosphorylation (IC50 = 6028 μM), as well as palmitic acid potentiated glucose-stimulated insulin secretion. The compound DC260126 blocks MIN6 β cells from palmitic acid-induced ER stress and apoptosis.
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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