Synonym: 2′,3′,4′-trihydroxy-flavone; 2-(2,3,4-Trihydroxyphenyl)-4H-1-Benzopyran-4-one
CAS Number: 144707-18-6
Empirical Formula (Hill Notation): C15H10O5
Molecular Weight: 270.24
Linear Formula: C15H10O5
Product Type: Chemical
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| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C15H10O5/c16-10-6-5-9(14(18)15(10)19)13-7-11(17)8-3-1-2-4-12(8)20-13/h1-7,16,18-19H |
| InChI key |
JJAXTFSPCLZPIW-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
[o]1c2c([c](cc1c3c(c(c(cc3)O)O)O)=O)cccc2 |
| solubility |
DMSO: 20 mg/mL, clear |
| storage temp. |
2-8°C |
| Application: |
2-D08 has been used as a small ubiquitin-like modifier (SUMO)ylation inhibitor. |
| Biochem/physiol Actions: |
2-D08 is a potent and cell-permeable inhibitor of sumoylation that block the transfer of SUMO (small ubiquitin-like modifier) from the E2 enzyme (Ubc9) thioester conjugate to the substrate. |
| Biochem/physiol Actions: |
2-D08 is a potent and cell-permeable inhibitor of sumoylation. |
| Packaging: |
5 mg in glass bottle |
| Hazard Codes |
Xn |
| Risk Statements |
22 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |