PBIT
SIGMA/SML1058 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 2514-30-9
Empirical Formula (Hill Notation): C14H11NOS
Molecular Weight: 241.31
Linear Formula: C14H11NOS
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C14H11NOS/c1-10-6-8-11 |
InChI key | KRXMYBAZKJBJAB-UHFFFAOYSA |
Quality Level | 100 |
solubility | DMSO: 10 mg/mL, clear (warmed) |
storage temp. | 2-8°C |
Biochem/physiol Actions: | S,S′-1,4-phenylenebis(1,2-et |
Biochem/physiol Actions: | PBIT is a potent inhibitor of JARID1B (KDM5B) histone lysine demethylase that inhibits removal of H3K4me3 in UACC-812 cells. PBIT inhibits proliferation of cells overexpressing JARID1B. PBIT is selective for JARID1 enzymes and does not inhibit demethylases UTX or JMJD3. |
Features and Benefits: | This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |