Celecoxib-NBD
SIGMA/SML1060 - ≥98% (HPLC)
Synonym: N-
Empirical Formula (Hill Notation): C25H20F3N7O5S
Molecular Weight: 587.53
Linear Formula: C25H20F3N7O5S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | yellow to orange |
form | powder |
Quality Level | 100 |
solubility | DMSO: 10 mg/mL, clear |
storage condition | protect from light |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Celecoxib-NBD is a flourescent COX2-specific inhibitor. The molecule binds to, and inhibits COX2 with an IC50 of 0.19 μM, and a selectivity index of 443 for COX2 vs. COX1. Celecoxib-NBD fluorescently labels COX2-expressing HCA-7 colon cells, but not COX2-negative HCT116 cells. |
Packaging: | 1, 5 mg in glass bottle |
Symbol | GHS06 |
Signal word | Danger |
Hazard statements | H301 - H413 |
Precautionary statements | P273 - P301 + P310 + P330 |
Hazard Codes | T |
Risk Statements | 25 |
Safety Statements | 45 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |