Celecoxib-NBD
SIGMA/SML1060 - ≥98% (HPLC)
Synonym: N-
Empirical Formula (Hill Notation): C25H20F3N7O5S
Molecular Weight: 587.53
Linear Formula: C25H20F3N7O5S
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | yellow to orange |
| form | powder |
| Quality Level | 100 ![]() |
| solubility | DMSO: 10 mg/mL, clear |
| storage condition | protect from light |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | Celecoxib-NBD is a flourescent COX2-specific inhibitor. |
| Biochem/physiol Actions: | Celecoxib-NBD is a flourescent COX2-specific inhibitor. The molecule binds to, and inhibits COX2 with an IC50 of 0.19 μM, and a selectivity index of 443 for COX2 vs. COX1. Celecoxib-NBD fluorescently labels COX2-expressing HCA-7 colon cells, but not COX2-negative HCT116 cells. |
| Packaging: | 1, 5 mg in glass bottle |
| Symbol | GHS06 |
| Signal word | Danger |
| Hazard statements | H301 - H413 |
| Precautionary statements | P273 - P301 + P310 + P330 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |


