PF-04856264
SIGMA/SML1061 - ≥98% (HPLC)
Synonym: 3-
CAS Number: 1235397-05-3
Empirical Formula (Hill Notation): C20H15N5O3S2
Molecular Weight: 437.49
MDL Number: MFCD28124397
Linear Formula: C20H15N5O3S2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to light brown |
form | powder |
InChI | 1S/C20H15N5O3S2/c1-25-17( |
InChI key | MKSKJVIBSRUWSZ-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | O=S(C(C=C1)=CC(C#N)=C1OC2 |
solubility | DMSO: 10 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | PF-04856264 is a potent, selective inhibitor of the human Nav1.7 voltage gated sodium channel (IC50 = 28 nM). PF-04856264 blocks mouse Nav1.7 (IC50 = 131 nM) but has low potency against the rat Nav1.7 channel (IC50 = 4.2 mM). |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS06 |
Signal word | Danger |
Hazard statements | H301 |
Precautionary statements | P301 + P310 |
Hazard Codes | T |
Risk Statements | 25 |
Safety Statements | 45 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |