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TR100

SIGMA/SML1065 - ≥98% (HPLC)

Synonym: 2-Cyano-3-[1-[3-(dimethylamino)propyl]-2-methyl-1H-indol-3-yl]-N-octyl-2-propenamide

CAS Number: 1128165-86-5
Empirical Formula (Hill Notation): C26H38N4O
Molecular Weight: 422.61
Linear Formula: C26H38N4O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1065-5MG 5 mg
 $153.00
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45-SML1065-25MG 25 mg
 $415.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C26H38N4O/c1-5-6-7-8-9-12-16-28-26(31)22(20-27)19-24-21(2)30(18-13-17-29(3)4)25-15-11-10-14-23(24)25/h10-11,14-15,19H,5-9,12-13,16-18H2,1-4H3,(H,28,31)/b22-19-
InChI key XXRLIGWROLDOLS-QOCHGBHMSA-N
Quality Level 100 
SMILES string CC1=C(/C=C(C#N)C(NCCCCCCCC)=O)C2=C(N1CCCN(C)C)C=CC=C2
solubility DMSO: 5 mg/mL, clear (warmed)
storage temp. 2-8°C
Biochem/physiol Actions: TR100 is a specific anti-tropomyosin agent that preferentially disrupts the actin cytoskeleton of tumor cells.
Biochem/physiol Actions: TR100 is a specific anti-tropomyosin agent that preferentially disrupts the actin cytoskeleton of tumor cells. TR100 selectively disrupts Tm5NM1/2 containing actin filaments. TR100 induces apoptosis in a panel of neural crest-derived tumor cell lines with no adverse effects on cardiac structure and function.
Packaging: 5, 25 mg in glass bottle
Hazard statements H413
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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