Advanced Search



ML240

SIGMA/SML1071 - ≥98% (HPLC)

Synonym: 2-(2-Amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine; CID-49830258

CAS Number: 1346527-98-7
Empirical Formula (Hill Notation): C23H20N6O
Molecular Weight: 396.44
MDL Number: MFCD28137687
Linear Formula: C23H20N6O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1071-5MG 5 mg
 $135.00
1/EA		 Add To Favorites
45-SML1071-25MG 25 mg
 $535.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color , white to yellow to light brown
form powder
InChI 1S/C23H20N6O/c1-30-19-13-7-10-16-20(19)27-23(28-21(16)25-14-15-8-3-2-4-9-15)29-18-12-6-5-11-17(18)26-22(29)24/h2-13H,14H2,1H3,(H2,24,26)(H,25,27,28)
InChI key NHAMBLRUUJAFOY-UHFFFAOYSA-N
Quality Level 100 
SMILES string NC1=NC2=C(C=CC=C2)N1C3=NC4=C(OC)C=CC=C4C(NCC5=CC=CC=C5)=N3
solubility DMSO: 5 mg/mL, clear (warmed)
storage temp. 2-8°C
Application: ML240 has been used as an inhibitor of D2 ATPase activity of valosin-containing protein.
Biochem/physiol Actions: ML240 is a selective, ATP-competetive inhibitor of AAA ATPase p97, also called valosine containing protein (VCP). The IC50 for p97 inhibition is 110 nM. ML240 rapidly induces activity of Caspases 3 and 7, leading to apoptosis. ML240 has potent antiproliferative activity towards NCI-60 cancer cell lines.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Year Price Updates

We are currently working diligently to update our website pricing information for the New Year. If you place an order, you will be acknowledged with any corrected pricing. If you'd like the most current information sooner, please don't hesitate to drop us an email or give us a call and we'd be happy to assist. Thank you for your patience while we are updating.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top