Synonym: (5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate; (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate; CID 9818479 maleate; PNU-95,666 maleate
CAS Number: 179386-44-8
Empirical Formula (Hill Notation): C11H13N3O · C4H4O4
Molecular Weight: 319.31
MDL Number: MFCD09832637
Linear Formula: C11H13N3O · C4H4O4
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C11H13N3O.C4H4O4/c1-12-8-5-7-3-2-4-9-10(7)14(6-8)11(15)13-9;5-3(6)1-2-4(7)8/h2-4,8,12H,5-6H2,1H3,(H,13,15);1-2H,(H,5,6)(H,7,8)/b;2-1-/t8-;/m1./s1 |
| InChI key |
VOJRMYBBPKNLLI-ORHWHDKWSA-N |
| optical activity |
[α]/D -22 to -32°, c = 1 in H2O |
| Quality Level |
100  |
| SMILES string |
O=C1N(C[C@H](NC)C2)C3=C2C=CC=C3N1.O=C(O)/C=CC(O)=O |
| solubility |
H2O: 10 mg/mL, clear |
| storage condition |
desiccated |
| storage temp. |
−20°C |
| Application: |
Sumanirole maleate has been used as a dopamine type 2 receptor (D2R) agonist to study its effects on spatial learning and memory in rats. |
| Biochem/physiol Actions: |
Sumanirole is a highly selective and potent dopamine D2 receptor agonist that decreased plasma prolactin levels and depressed dopamine neuron firing rates in the substantia nigra pars compacta. Sumanirole potently stimulates locomotor activity in in animal models of Parkinson’s disease. |
| Features and Benefits: |
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Packaging: |
5, 25 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
−20°C |
| UNSPSC |
12352200 |
