BC8-15

SIGMA/SML1097 - ≥98% (HPLC)

Synonym: 3-[(3-Ethyl-1,2,4-triazolo[4,3-c]quinazolin-5-yl)amino]-benzoic acid

CAS Number: 950385-77-0
Empirical Formula (Hill Notation): C₁₈H₁₅N₅O₂
Molecular Weight: 333.34
Linear Formula: C₁₈H₁₅N₅O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML1097-5MG	5 mg	$149.00 1/EA		Add To Favorites
45-SML1097-25MG	25 mg	$0.00 1/EA CALL FOR PRICE		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C18H15N5O2/c1-2-15-21-22-16-13-8-3-4-9-14(13)20-18(23(15)16)19-12-7-5-6-11(10-12)17(24)25/h3-10H,2H2,1H3,(H,19,20)(H,24,25)
InChI key	INDKHRIZOIEPIG-UHFFFAOYSA-N
Quality Level	100
SMILES string	CCC1=NN=C2N1C(NC3=CC=CC(C(O)=O)=C3)=NC4=CC=CC=C42
solubility	DMSO: 20 mg/mL, clear
storage temp.	2-8°C

Biochem/physiol Actions:	BC8-15 has the ability to block PDE8A (phosphodiesterase 8A) and PDE4A (phosphodiesterase 4A) with IC50 values of 280 and 220 nM. It helps to increase the synthesis of the steroid from both primary Leydig cells and MA-10 cells.
Biochem/physiol Actions:	BC8-15 is a potent PDE4/8 inhibitor that elevates steroidogenesis in mouse Leydig cells.
Features and Benefits:	This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	41106305

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