Synonym: 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid sodium salt; Nedocromil disodium salt
CAS Number: 69049-74-7
Empirical Formula (Hill Notation): C19H15NO7 · 2 Na
Molecular Weight: 415.30
Linear Formula: C19H15NO7 · 2 Na
Product Type: Chemical
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| assay |
≥98% (HPLC) |
| color |
, white to beige to brown |
| form |
powder |
| InChI |
1S/C19H17NO7.2Na/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11;;/h6-8H,3-5H2,1-2H3,(H,23,24)(H,25,26);;/q;2*+1/p-2 |
| InChI key |
JQEKDNLKIVGXAU-UHFFFAOYSA-L |
| Quality Level |
100  |
| SMILES string |
[Na+].[Na+].[n]1(c2c([c](cc1C(=O)[O-])=O)cc3c([o]c(c[c]3=O)C(=O)[O-])c2CCC)CC |
| solubility |
H2O: 20 mg/mL, clear |
| storage condition |
desiccated |
| storage temp. |
2-8°C |
| Biochem/physiol Actions: |
Nedocromil is a mast cell stabilizer and anti-inflammatory and anti-allergic drug. |
| Biochem/physiol Actions: |
Nedocromil is a mast cell stabilizer and anti-inflammatory and anti-allergic drug. Nedocromil inhibits the degranulation of mast cells, and prevents the activation of and mediator release from a variety of inflammatory cell types. Nedocromil inhibits release of histamine, leukotriene C4, and prostaglandin D2, but has no antihistamine, bronchodilator, or corticosteroid activity itself. |
| Biochem/physiol Actions: |
Nedocromil is considered to be more effective in treating asthma compared to a placebo. |
| Packaging: |
10, 50 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |