Advanced Search



Darifenacin hydrobromide

SIGMA/SML1102 - ≥98% (HPLC)

Synonym: (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide hydrobromide; UK 88525-04

CAS Number: 133099-07-7
Empirical Formula (Hill Notation): C28H30N2O2 · HBr
Molecular Weight: 507.46
MDL Number: MFCD08141803
Linear Formula: C28H30N2O2 · HBr
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1102-10MG 10 mg
 $70.80
1/EA		 Add To Favorites
45-SML1102-50MG 50 mg
 $303.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C28H30N2O2.BrH/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26;/h1-12,19,25H,13-18,20H2,(H2,29,31);1H/t25-;/m1./s1
InChI key UQAVIASOPREUIT-VQIWEWKSSA-N
optical activity [α]/D +41 to +49°, c = 1 in methylene chloride
Quality Level 100 
SMILES string O=C(N)C([C@H]1CN(CCC2=CC=C(OCC3)C3=C2)CC1)(C4=CC=CC=C4)C5=CC=CC=C5.Br
solubility DMSO: 20 mg/mL, clear
storage condition desiccated
storage temp. −20°C
Application: Darifenacin hydrobromide has been used to inject experimental animals.
Biochem/physiol Actions: Darifenacin hydrobromide is an antispasmodic muscarinic antagonist, selective for blocking the M3 muscarinic acetylcholine receptor, which is primarily responsible for bladder muscle contractions. Darifenacin hydrobromide has 9 and 12-fold greater affinity for M3 compared to M1 and M5, respectively, and 59-fold greater affinity for M3 compared to both M2 and M4. Darifenacin is used clinically to treat urinary incontinence and overactive bladder syndrome.
Biochem/physiol Actions: Darifenacin hydrobromide is an antispasmodic muscarinic antagonist, selective for blocking the M3 muscarinic acetylcholine receptor.
Features and Benefits: This compound is a featured product for Neuroscience research. Click here  to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
General description: Darifenacin is a muscarinic receptor antagonist. It is an extended release tablet that has 7.5 mg or 15 mg darifenacin as its hydrobromide salt.
Packaging: 10, 50 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Year Price Updates

We are currently working diligently to update our website pricing information for the New Year. If you place an order, you will be acknowledged with any corrected pricing. If you'd like the most current information sooner, please don't hesitate to drop us an email or give us a call and we'd be happy to assist. Thank you for your patience while we are updating.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top