Synonym: 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one; 2-Amino-9-[(1S,3R,4S)-4-hydroxy-3-hydroxymethyl-2-methylene-cyclopentyl]-3,9-dihydro-purin-6-one; BMS 200475; SQ 34,676
CAS Number: 142217-69-4
Empirical Formula (Hill Notation): C12H15N5O3
Molecular Weight: 277.28
MDL Number: MFCD11046562
Linear Formula: C12H15N5O3
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7-,8-/m0/s1 |
| InChI key |
QDGZDCVAUDNJFG-FXQIFTODSA-N |
| optical activity |
[α]/D +25 to +40°, c = 0.2 in H2O |
| Quality Level |
100  |
| SMILES string |
O=C1C2=C(N([C@H]3C[C@H](O)[C@@H](CO)C3=C)C=N2)NC(N)=N1 |
| solubility |
H2O: 0.5 mg/mL, clear (warmed) |
| storage condition |
desiccated |
| storage temp. |
−20°C |
| Biochem/physiol Actions: |
Entecavir is an antiviral guanine analog that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Entecavir is used to treat hepatitis B. |
| Biochem/physiol Actions: |
Entecavir is an antiviral guanine analog that inhibits reverse transcription, DNA replication and transcription. |
| Biochem/physiol Actions: |
Entecavir is used as an effective drug to treat lamivudine-refractory patients with chronic hepatitis B virus (CHB) at a dose of 1 mg daily. |
| Packaging: |
10, 50 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
−20°C |
| UNSPSC |
51111800 |
