Synonym: N-(6-Methyl-2-benzothiazolyl)-2-[[3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl]thio]-acetamide
CAS Number: 686772-17-8
Empirical Formula (Hill Notation): C23H20N4O3S3
Molecular Weight: 496.62
Linear Formula: C23H20N4O3S3
Product Type: Chemical
| assay |
≥95% (HPLC) |
| color |
white to light brown |
| form |
powder |
| InChI |
1S/C23H20N4O3S3/c1-13-7-8-14-18(11-13)33-22(24-14)26-19(28)12-32-23-25-15-9-10-31-20(15)21(29)27(23)16-5-3-4-6-17(16)30-2/h3-8,11H,9-10,12H2,1-2H3,(H,24,26,28) |
| InChI key |
RHUJMHOIQBDFQR-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
O=C1C2=C(CCS2)N=C(SCC(NC3=NC(C=CC(C)=C4)=C4S3)=O)N1C5=C(OC)C=CC=C5 |
| solubility |
DMSO: 0.5 mg/mL, clear (warmed) |
| storage temp. |
−20°C |
| Biochem/physiol Actions: |
IWP-4 blocks Wnt family member 5a. It blocks Wnt protein secretion and prevents the canonical and non-canonical signaling pathways. |
| Biochem/physiol Actions: |
IWP-4 is a potent inhbitor of the Wnt pathway regulatory protein porupine (Porcn). |
| Biochem/physiol Actions: |
IWP-4 is a potent inhbitor of the Wnt pathway regulatory protein porupine (Porcn). IWP-4 blocks palmitylation, and subsquent secretion and activity of Wnt. IWP-4 induces the differentiation of human pluripotent stem cells into cardiomyocytes. |
| Packaging: |
5, 25 mg in glass bottle |
| Symbol |
 GHS07 |
| Signal word |
Warning |
| Hazard statements |
H302 |
| Hazard Codes |
Xn |
| Risk Statements |
22 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥95% (HPLC) |
| Storage Temp. |
−20°C |
| UNSPSC |
12352200 |
