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Hepcidin-25 (human) trifluoroacetate salt

SIGMA/SML1118 - ≥95% (HPLC)

Synonym: DTHFPICIFCCGCCHRSKCGMCCKT trifluoroacetate salt; H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH trifluoroacetate salt; Hepc25 (human); LEAP-1 (Liver-Expressed Antimicrobial Peptide) (human) trifluoroacetate salt; PLTR (Putative Liver Tumor Regressor ) (human)

CAS Number: 342809-17-0 (free base)
Empirical Formula (Hill Notation): C113H170N34O31S9 · xC2HF3O2
Molecular Weight: 2789.35 (free base basis)
Linear Formula: C113H170N34O31S9 · xC2HF3O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1118-500UG 500 µg
 $1140.00
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assay ≥95% (HPLC)
color white to off-white
form powder
Quality Level 100 
shipped in wet ice
storage temp. −20°C
Amino Acid Sequence: H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH trifluoroacetate salt
Biochem/physiol Actions: Hepcidin is the master regulator of iron homeostasis with anti-inflammatory and antimicrobial activity.
Biochem/physiol Actions: Hepcidin is the master regulator of iron homeostasis. Hepcidin is found in liver, but also widely distributed in brain, where it may play a role in preventing iron-related neurodegeneration. Hepcidin has anti-inflammatory and antimicrobial activity.
Biochem/physiol Actions: Hepcidin-25 is the major isoform of hepcidin. hepcidin‐25 with reticulocyte hemoglobin content (CHr) in the hepcidin‐25 plot helps to differentiate DA can be differentiated iron‐deficient anemia (IDA) from the anemia of chronic disease (ACD) and the combined state of ACD/IDA. Mutation in the hepcidin gene is associated with the development of severe juvenile hemochromatosis.
Packaging: 500 μg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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