Synonym: (3,5,14)-21,23-epoxy24-Norchola-20,22-diene-3,14,17-triol; PST 2238
CAS Number: 156722-18-8
Empirical Formula (Hill Notation): C23H34O4
Molecular Weight: 374.51
Linear Formula: C23H34O4
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
white to beige |
form |
powder |
InChI |
1S/C23H34O4/c1-20-8-5-17(24)13-15(20)3-4-19-18(20)6-9-21(2)22(25,10-11-23(19,21)26)16-7-12-27-14-16/h7,12,14-15,17-19,24-26H,3-6,8-11,13H2,1-2H3/t15-,17+,18+,19-,20+,21-,22+,23+/m1/s1 |
InChI key |
AEAPORIZZWBIEX-DTBDINHYSA-N |
Quality Level |
100 |
solubility |
DMSO: 20 mg/mL, clear |
storage temp. |
−20°C |
Biochem/physiol Actions: |
Rostafuroxin is a derivative of digitoxigenin. It protects animal models against podocyte lesions and proteinuria by counteracting mutant β-adducin and ouabain-mediated effects. |
Biochem/physiol Actions: |
Rostafuroxin is a digitoxygenin derivative that selectively antagonizes the effects of endogenous ouabain on the Na+,K+-ATPase, which maintains sodium and potassium ion gradients across plasma membranes. Rostafuroxin lowers blood pressure (BP) in animal models of hypertension. |
Packaging: |
5, 25 mg in glass bottle |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
−20°C |
UNSPSC |
12352200 |