GSK137647A
SIGMA/SML1152 - ≥98% (HPLC)
Synonym: 4-
CAS Number: 349085-82-1
Empirical Formula (Hill Notation): C16H19NO3S
Molecular Weight: 305.39
MDL Number: MFCD02007969
Linear Formula: C16H19NO3S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C16H19NO3S/c1-11-9-12( |
InChI key | FQUAFMNPXPXOJE-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | CC1=C(NS(C2=CC=C(OC)C=C2) |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | GSK137647A is a selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), which is involved in long-chain fatty acid stimulated GLP-1 secretion and has been implicated in glucose homeostasis, adiposity, and regulation of the anti-inflammatory response. GSK137647A has pEC50 values of 6.3, 6.2, and 6.1 for human, mouse and rat FFA4, and pEC50 values < 4.5 for all three species for FFA1, FFA2, and FFA3. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |