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GSK137647A

SIGMA/SML1152 - ≥98% (HPLC)

Synonym: 4-Methoxy-N-(2,4,6-trimethylphenyl)-benzenesulfonamide; N-Mesityl-4-methoxybenzenesulfonamide

CAS Number: 349085-82-1
Empirical Formula (Hill Notation): C16H19NO3S
Molecular Weight: 305.39
MDL Number: MFCD02007969
Linear Formula: C16H19NO3S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML1152-5MG 5 mg
$118.00
1/EA
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45-SML1152-25MG 25 mg
$476.00
1/EA
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C16H19NO3S/c1-11-9-12(2)16(13(3)10-11)17-21(18,19)15-7-5-14(20-4)6-8-15/h5-10,17H,1-4H3
InChI key FQUAFMNPXPXOJE-UHFFFAOYSA-N
Quality Level 100 
SMILES string CC1=C(NS(C2=CC=C(OC)C=C2)(=O)=O)C(C)=CC(C)=C1
solubility DMSO: 20 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: GSK137647A is a selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), which is involved in long-chain fatty acid stimulated GLP-1 secretion and has been implicated in glucose homeostasis, adiposity, and regulation of the anti-inflammatory response. GSK137647A has pEC50 values of 6.3, 6.2, and 6.1 for human, mouse and rat FFA4, and pEC50 values < 4.5 for all three species for FFA1, FFA2, and FFA3.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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