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GSA-10

SIGMA/SML1171 - ≥98% (HPLC)

Synonym: 4-[[(1-Hexyl-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl)carbonyl]amino]-benzoic acid propyl ester

CAS Number: 300833-95-8
Empirical Formula (Hill Notation): C26H30N2O5
Molecular Weight: 450.53
MDL Number: MFCD01128015
Linear Formula: C26H30N2O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1171-5MG 5 mg
 $121.00
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assay ≥98% (HPLC)
color white to light brown
form powder
InChI 1S/C26H30N2O5/c1-3-5-6-9-16-28-21-11-8-7-10-20(21)23(29)22(25(28)31)24(30)27-19-14-12-18(13-15-19)26(32)33-17-4-2/h7-8,10-15,29H,3-6,9,16-17H2,1-2H3,(H,27,30)
InChI key MDLUYYGRCGDKGL-UHFFFAOYSA-N
Quality Level 100 
SMILES string OC(C1=CC=CC=C1N2CCCCCC)=C(C(NC3=CC=C(C(OCCC)=O)C=C3)=O)C2=O
solubility DMSO: 0.5 mg/mL, clear (warmed)
storage temp. 2-8°C
Biochem/physiol Actions: GSA-10 is a novel, potent activator of the smoothened receptor (Smo).
Biochem/physiol Actions: GSA-10 is a novel, potent activator of the smoothened receptor (Smo). GSA-10 binds to Smo at a unique site compared to agonists such as SAG and purmorphamine, and is not affected by the Smo antagonist cyclopamine. GSA-10 promotes the differentiation of mesenchymal pluripotent C3H10T1/2 cells into osteoblasts.
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 51111800

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