Lubiprostone
SIGMA/SML1173 - ≥98% (HPLC)
Synonym: (11a,15R)
CAS Number: 136790-76-6
Empirical Formula (Hill Notation): C20H32F2O5
Molecular Weight: 390.46
Linear Formula: C20H32F2O5
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C20H32F2O5/c1-2-3-11-1 |
InChI key | WGFOBBZOWHGYQH-DKYLXPRQSA |
Quality Level | 100 |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | Lubiprostone helps to enhance intestinal permeability in humans. Hence it may inhibit leaky gut syndrome. |
Biochem/physiol Actions: | Lubiprostone is a bicyclic fatty acid that activates ClC-2 and CFTR chloride channels. Some reports suggest that lubiprostone opens CFTR or both CFTR and ClC-2 through interactions with the prostaglandin receptor EP4. Lubiprostone is used clinically to treat idiopathic chronic constipation and irritible bowel syndrome. |
Packaging: | 10, 50 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H315 - H319 - H335 |
Precautionary statements | P302 + P352 - P305 + P351 + P338 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |