GGTI-286 dihydrochloride
SIGMA/SML1186 - ≥90% (HPLC)
Synonym: (R)
CAS Number: 171744-11-9 (free base)
Empirical Formula (Hill Notation): C23H31N3O3S · 2HCl
Molecular Weight: 502.50
Linear Formula: C23H31N3O3S · 2HCl
Product Type: Chemical
assay | ≥90% (HPLC) |
color | white to light brown |
form | powder |
shipped in | wet ice |
solubility | DMSO: 20 mg/mL, clear |
storage condition | desiccated |
storage temp. | −20°C |
Biochem/physiol Actions: | GGTI-286 is a cell permeable, potent and selective inhibitor of geranylgeranyltransferase I (GGTase I) that selectively disrupts oncogenic K-Ras4B. New study shows that GGTI-286 reduces nuclear localization of β-catenin. |
Other Notes: | Air sensitive; dessicant. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H315 - H319 - H335 |
Precautionary statements | P305 + P351 + P338 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥90% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |