PYZD-4409
SIGMA/SML1188 - ≥98% (HPLC)
Synonym: 1-
CAS Number: 423148-78-1
Empirical Formula (Hill Notation): C14H7ClFN3O5
Molecular Weight: 351.67
MDL Number: MFCD01828668
Linear Formula: C14H7ClFN3O5
Product Type: Chemical
assay | ≥98% (HPLC) |
color | , white to very dark brown |
form | powder |
InChI | 1S/C14H7ClFN3O5/c15-10-5- |
InChI key | MSYMKEYWUWVZQY-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | FC1=CC=C(N2C(C(C(N2)=O)=C |
solubility | DMSO: 10 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | PYZD-4409 inhibts ATP-dependent activation of human ubiquitin activating enzyme E1 with an IC50 of 20 mM. PYZD-4409 induces cell death, and inhbits clonogenic growth of leukemia and myeloma cell lines, and inhibits leukemia xenograft tumor growth in mice. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS06 |
Signal word | Danger |
Hazard statements | H301 - H315 - H319 - H335 |
Precautionary statements | P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |