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SU1498

SIGMA/SML1193 - ≥98% (HPLC)

Synonym: (2E)-2-Cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-2-propenamide; (E)-N-(3-Phenylpropyl)-cyano-3,5-diisopropyl-4-hydroxycinnamamide; AG-1498; SU 1498; Tyrphostin SU 1498; Tyrphostin SU1498

CAS Number: 168835-82-3
Empirical Formula (Hill Notation): C25H30N2O2
Molecular Weight: 390.52
Linear Formula: C25H30N2O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1193-5MG 5 mg
 $130.00
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45-SML1193-25MG 25 mg
 $520.00
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assay ≥98% (HPLC)
color white to beige
form powder
Quality Level 100 
solubility DMSO: 10 mg/mL, clear
storage condition desiccated
storage temp. −20°C
Biochem/physiol Actions: SU1498 is a potent and selective inhibitor of the VEGFR2 receptor kinase, Flk-1 with an IC50 value of 700 nM. SU1498 is a very weak inhibitor of PDGFR-kinase, EGFR-kinase and HER-2 kinase with IC50 values > 50 μM. SU1498 has been used to study the role of VEGFR2 (Flk-1) in a variety of biological activities including angiogenesis, tumor growth inhibition, and stem cell proliferation.
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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