Synonym: (3aS)-2-[(3S)-Quinuclidin-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one hydrochloride; (3aS)-2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-Benz[de]isoquinolin-1-one hydrochloride (1:1); RS 25259-197
CAS Number: 135729-62-3
Empirical Formula (Hill Notation): C19H24N2O · HCl
Molecular Weight: 332.87
MDL Number: MFCD00939524
Linear Formula: C19H24N2O · HCl
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
white to beige |
form |
powder |
InChI |
1S/C19H24N2O.ClH/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20;/h2,4,6,13,15,17H,1,3,5,7-12H2;1H/t15-,17-;/m1./s1 |
InChI key |
OLDRWYVIKMSFFB-SSPJITILSA-N |
optical activity |
[α]/D -90 to -110°, c = 0.4 in H2O |
Quality Level |
100 |
SMILES string |
O=C1N([C@H]2C3CCN(CC3)C2)C[C@]4([H])C5=C1C=CC=C5CCC4.[H]Cl |
solubility |
H2O: 20 mg/mL, clear |
storage condition |
desiccated |
|
protect from light |
storage temp. |
−20°C |
Biochem/physiol Actions: |
Palonosetron is a potent and selective 5-HT3 receptor antagonist (Aloxi) used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). |
Packaging: |
10, 50 mg in glass bottle |
Symbol |
GHS07 |
Signal word |
Warning |
Hazard statements |
H302 |
Precautionary statements |
P301 + P312 + P330 |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
−20°C |
UNSPSC |
12352200 |