Synonym: (6R)-6-[[(4-Chlorophenyl)sulfonyl]amino]-5,6,7,8-tetrahydro-2-methyl-1-Naphthalenepropanoic acid; (R)-6-[[(4-Chlorophenyl)sulfonyl]amino]-5,6,7,8-tetrahydro-2-methyl-1-Naphthalenepropanoic acid; S18886
CAS Number: 165538-40-9
Empirical Formula (Hill Notation): C20H22ClNO4S
Molecular Weight: 407.91
Linear Formula: C20H22ClNO4S
Product Type: Chemical
assay |
≥95% (HPLC) |
color |
white to beige |
form |
powder |
InChI |
1S/C20H22ClNO4S/c1-13-2-3-14-12-16(6-9-19(14)18(13)10-11-20(23)24)22-27(25,26)17-7-4-15(21)5-8-17/h2-5,7-8,16,22H,6,9-12H2,1H3,(H,23,24)/t16-/m0/s1 |
InChI key |
HWEOXFSBSQIWSY-INIZCTEOSA-N |
optical activity |
[α]/D 25 to 31°, c = 1 in DMSO |
Quality Level |
100 |
SMILES string |
O=S(N[C@@H]1CC2=CC=C(C)C(CCC(O)=O)=C2CC1)(C3=CC=C(Cl)C=C3)=O |
solubility |
DMSO: 10 mg/mL, clear |
storage condition |
desiccated |
storage temp. |
−20°C |
Biochem/physiol Actions: |
Terutroban is a highly selective and long-acting thromboxane/prostaglandin endoperoxide receptor (TPr) antagonist. The compound Terutroban blocks thromboxane induced platelet aggregation and vasoconstriction. Terutroban prevents vascular wall proliferation and atherogenesis, increases anti-oxidant enzymes like glutathione peroxidase, and has anti-inflammatory properties. |
Packaging: |
10, 50 mg in glass bottle |
Purity |
≥95% (HPLC) |
Storage Temp. |
−20°C |
UNSPSC |
12352200 |