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Terutroban

SIGMA/SML1198 - ≥95% (HPLC)

Synonym: (6R)-6-[[(4-Chlorophenyl)sulfonyl]amino]-5,6,7,8-tetrahydro-2-methyl-1-Naphthalenepropanoic acid; (R)-6-[[(4-Chlorophenyl)sulfonyl]amino]-5,6,7,8-tetrahydro-2-methyl-1-Naphthalenepropanoic acid; S18886

CAS Number: 165538-40-9
Empirical Formula (Hill Notation): C20H22ClNO4S
Molecular Weight: 407.91
Linear Formula: C20H22ClNO4S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1198-10MG 10 mg
 $103.00
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assay ≥95% (HPLC)
color white to beige
form powder
InChI 1S/C20H22ClNO4S/c1-13-2-3-14-12-16(6-9-19(14)18(13)10-11-20(23)24)22-27(25,26)17-7-4-15(21)5-8-17/h2-5,7-8,16,22H,6,9-12H2,1H3,(H,23,24)/t16-/m0/s1
InChI key HWEOXFSBSQIWSY-INIZCTEOSA-N
optical activity [α]/D 26 to 34°, c = 1 in DMSO
Quality Level 100 
SMILES string O=S(N[C@@H]1CC2=CC=C(C)C(CCC(O)=O)=C2CC1)(C3=CC=C(Cl)C=C3)=O
solubility DMSO: 10 mg/mL, clear
storage condition desiccated
storage temp. −20°C
Biochem/physiol Actions: Terutroban is a highly selective and long-acting thromboxane/prostaglandin endoperoxide receptor (TPr) antagonist.
Biochem/physiol Actions: Terutroban is a highly selective and long-acting thromboxane/prostaglandin endoperoxide receptor (TPr) antagonist. The compound Terutroban blocks thromboxane induced platelet aggregation and vasoconstriction. Terutroban prevents vascular wall proliferation and atherogenesis, increases anti-oxidant enzymes like glutathione peroxidase, and has anti-inflammatory properties.
Packaging: 10, 50 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H315 - H319 - H335
Precautionary statements P261 - P305 + P351 + P338
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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