2-PMAP
SIGMA/SML1203 - ≥98% (HPLC)
Synonym: (2-
CAS Number: 102212-26-0
Empirical Formula (Hill Notation): C12H12N2O
Molecular Weight: 200.24
MDL Number: MFCD24550644
Linear Formula: C12H12N2O
Product Type: Chemical
assay | ≥98% (HPLC) |
color | , white to dark brown |
form | powder |
InChI | 1S/C12H12N2O/c15-12-7-2-1 |
InChI key | GXJRVWZNMZGWAQ-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | OC1=CC=CC=C1NCC2=NC=CC=C2 |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | 2-PMAP is a brain penetrant inhibitor of amyloid precursor protein (APP) production. 2-PMAP lowers levels of the amyloid precursor protein (APP) in CHO APP751SW cells. Also it reduces brain level of APP in mice model. 2-PMAP exhibits no cellular toxicity up to 100 μM. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P301 + P312 + P330 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |