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Almotriptan malate

SIGMA/SML1210 - ≥98% (HPLC)

Synonym: 3-[2-(Dimethylamino)ethyl]-5-(pyrrolidin-1-ylsulfonylmethyl )-1H-indole malate; PNU 180638

CAS Number: 181183-52-8
Empirical Formula (Hill Notation): C17H25N3O2S · C4H6O5
Molecular Weight: 469.55
Linear Formula: C17H25N3O2S · C4H6O5
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML1210-10MG 10 mg
$142.00
1/EA
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45-SML1210-50MG 50 mg
$561.00
1/EA
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C17H25N3O2S.C4H6O5/c1-19(2)10-7-15-12-18-17-6-5-14(11-16(15)17)13-23(21,22)20-8-3-4-9-20;5-2(4(8)9)1-3(6)7/h5-6,11-12,18H,3-4,7-10,13H2,1-2H3;2,5H,1H2,(H,6,7)(H,8,9)
InChI key QHATUKWEVNMHRY-UHFFFAOYSA-N
Quality Level 100 
solubility H2O: 10 mg/mL, clear
storage condition desiccated
storage temp. −20°C
Application: Almotriptan at an oral dose of 12.5 mg, is recommended to be safe for treating migraine.
Application: Almotriptan is a serotonin 5HT-1B/1D-receptor agonist; antimigraine.
Biochem/physiol Actions: Almotriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Almotriptan has low nanomolar affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower. Affinity for 5-HT(7) and 5-HT(1A) receptors was approximately 40 and 60 times lower than that for 5-HT(1B/1D) receptors, respectively.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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