SMANT hydrochloride
SIGMA/SML1211 - ≥98% (HPLC)
Synonym: N-
CAS Number: 1177600-74-6
Empirical Formula (Hill Notation): C16H23BrN2O · HCl
Molecular Weight: 375.73
MDL Number: MFCD06620515
Linear Formula: C16H23BrN2O · HCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C16H23BrN2O.ClH/c1-12- |
InChI key | XQESCHFXROUCOQ-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | BrC1=CC=C(NC(CCN2CC(C)CC( |
solubility | H2O: 1 mg/mL, clear (warmed) |
storage condition | desiccated |
storage temp. | 2-8°C |
Biochem/physiol Actions: | SMANT is a Hedgehog pathway antagonist, a Smoothened antagonist that behaves similarly against normal cancer smoothened and the M2 mutant. In a study comparing activities among the currently known smoothened/Hedgehog antagonists, SMANT behaves differently, binding to another Smo site different to that bound by other compounds. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS09 |
Hazard statements | H411 |
Precautionary statements | P273 - P391 - P501 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 51111800 |