Torin2
SIGMA/SML1224 - ≥98% (HPLC)
Synonym: 9-
CAS Number: 1223001-51-1
Empirical Formula (Hill Notation): C24H15F3N4O
Molecular Weight: 432.40
Linear Formula: C24H15F3N4O
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 |
solubility | DMSO: 5 mg/mL, clear (warmed) |
storage temp. | 2-8°C |
Application: | Torin2 has been used: • to examine its effect on LC3B-II levels in BORCS5- KO cells • to determine its potent activity (IC50 less than 1 μM) against A2780-cis ovarian cancer cells • in western blot analysis |
Biochem/physiol Actions: | Torin2 is a highly potent and selective ATP-competitive mTOR inhibitor. Torin2 has an IC50 of 0.25 nM and 800-fold greater selectivity for mTOR than PI3K. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |