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HAMNO

SIGMA/SML1234 - ≥98% (HPLC)

Synonym: (1Z)-1-[(2-Hydroxyanilino)methylidene]naphthalen-2-one; 1-[[(2-Hydroxyphenyl)imino]methyl]-2-naphthalenol; CID 6335338; MLS000737724; NS C111847; NSC111847

CAS Number: 138736-73-9
Empirical Formula (Hill Notation): C17H13NO2
Molecular Weight: 263.29
Linear Formula: C17H13NO2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1234-5MG 5 mg
 $121.00
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45-SML1234-25MG 25 mg
 $475.00
1/EA		 Add To Favorites
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color yellow to orange
form powder
InChI key NADCEWZYITXLKJ-KAMYIIQDSA-N
Quality Level 100 
SMILES string N(c3c(cccc3)O)C=C1c2c(cccc2)C=CC1=O
solubility DMSO: 10 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: HAMNO is a potent and selective inhibitor of replication protein A (RPA) interactions with proteins involved in the replication stress response. HAMNO binds the N-terminal domain of RPA70 and inhibits both ATR autophosphorylation and phosphorylation of RPA32 Ser33 by ATR. HAMNO enhances DNA replication stress in cancer cells and slow tumor growth in vivo.
Biochem/physiol Actions: HAMNO is a potent and selective inhibitor of replication protein A (RPA) interactions.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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