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(−)-Nicotine hydrogen tartrate salt

SIGMA/SML1236 - ≥98% (HPLC)

Synonym: (−)-Nicotine ditartrate; (−)-1-Methyl-2-(3-pyridyl)pyrrolidine (+)-bitartrate salt

CAS Number: 65-31-6
Empirical Formula (Hill Notation): C10H14N2 · 2C4H6O6
Molecular Weight: 462.41
EC Number: 200-607-2
Linear Formula: C10H14N2 · 2C4H6O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1236-50MG 50 mg
 $91.20
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45-SML1236-1G 1 g
 $1480.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: SML1236-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: SML1236-50MG

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C10H14N2.CH4/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;/h2,4,6,8,10H,3,5,7H2,1H3;1H4/t10-;/m0./s1
InChI key RYYKFQGHMYGLEL-PPHPATTJSA-N
optical activity [α]/D +20 to +26°, c = 1.0 in water
Quality Level 100 
SMILES string CN1CCC[C@H]1C2=CC=CN=C2.C
solubility H2O: 20 mg/mL, clear
storage condition desiccated
storage temp. room temp
Application: (−)-Nicotine hydrogen tartrate salt has been used as an agonist for acetylcholine receptor (AChr).
Application: (−)-Nicotine hydrogen tartrate salt has been used in intracellular calcium imaging.
Biochem/physiol Actions: NHT is considered to be more stable than nicotine. Nicotine is highly addictive drug and is indirectly but strongly associated with tobacco related diseases. It helps to discontinue smoking. Nicotine might serve as a therapeutic agent in treating Alzheimer’s disease, Parkinson’s disease and ulcerative colitis.
Biochem/physiol Actions: Prototype nicotinic acetylcholine receptor agonist; naturally occurring isomer.
Packaging: 1 g in glass bottle
Packaging: 50 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352210

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