Fondaparinux sodium

SIGMA/SML1240 - ≥95% (HPLC)

Synonym: Fondaparin sodium; Methyl O-2-deoxy-6-O-sulfo-2-(sulfoamino)-α-D-glucopyranosyl-(14)-O-β-D-glucopyranuronosyl-(14)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-α-D-glucopyranosyl-(14)-O-2-O-sulfo-α-L-idopyranuronosyl-(14)-2-deoxy-2-(sulfoamino)-α-D-glucopyranoside 6-(hydrogen sulfate) sodium salt; SR-90107A

CAS Number: 114870-03-0
Empirical Formula (Hill Notation): C₃₁H₄₃N₃O₄₉S₈ · 10Na
Molecular Weight: 1728.08
Linear Formula: C₃₁H₄₃N₃O₄₉S₈ · 10Na
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1240-5MG	5 mg	$121.00 1/EA	Add To Favorites
45-SML1240-25MG	25 mg	$475.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (HPLC)
color	white to beige
form	powder
InChI	1S/C31H53N3O49S8.10Na/c1-69-27-9(33-85(48,49)50)13(37)17(6(74-27)3-71-88(57,58)59)76-31-22(83-91(66,67)68)16(40)21(24(81-31)26(43)44)79-29-10(34-86(51,52)53)19(82-90(63,64)65)18(7(75-29)4-72-89(60,61)62)77-30-15(39)14(38)20(23(80-30)25(41)42)78-28-8(32-84(45,46)47)12(36)11(35)5(73-28)2-70-87(54,55)56;;;;;;;;;;/h5-24,27-40H,2-4H2,1H3,(H,41,42)(H,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68);;;;;;;;;;/q;10*+1/p-10/t5-,6-,7-,8-,9-,10-,11-,12-,13-,14-,15-,16+,17-,18-,19-,20+,21+,22-,23+,24-,27+,28-,29-,30-,31-;;;;;;;;;;/m1........../s1
InChI key	XEKSTYNIJLDDAZ-JASSWCPGSA-D
optical activity	[α]/D 42.0 to 55.0° (c = 0.5 in water)
Quality Level	100
shipped in	wet ice
SMILES string	[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[S](=O)(=O)(N[C@H]1[C@H](O[C@@H]([C@H]([C@@H]1O[S](=O)(=O)[O-])O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O[C@H]5O[C@@H]([C@H]([C@@H]([C@H]5N[S](=O)(=O)[O-])O)O)CO[S](=O)(=O)[O-])C(=O)[O-])CO[S](=O)(
solubility	H₂O: 20 mg/mL, clear
storage condition	desiccated
storage temp.	−20°C

Application:	Fondaparinux sodium has been used to test its neutralizing effect towards enterovirus D68-947 infection. It may be used in ultraviolet photodissociation (UVPD) measurements.
Biochem/physiol Actions:	Fondaparinux sodium is an antithrombotic anticoagulant, a Factor Xa inhibitor.
Biochem/physiol Actions:	Fondaparinux sodium is an antithrombotic anticoagulant, a Factor Xa inhibitor. Fondaparinux sodium is chemically related to low molecular weight heparins. Its pentasaccharide structure corresponds to the antithrombin III (ATIII) binding site of heparin. Fondaparinux sodium binding at this site potentiates the natural inhibitory effect of ATIII against factor Xa by a factor of approximately 300, which results in inhibition of thrombin generation.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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