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Treosulfan

SIGMA/SML1252 - ≥98% (HPLC)

Synonym: (2S,3S)-Butanetetraol 1,4-dimesylate; (2S,3S)-Threitol 1,4-bismethanesulfonate; L-Threitol 1,4-bis(methanesulfonate); NSC 39069; Threosulphan; Treosulphan

CAS Number: 299-75-2
Empirical Formula (Hill Notation): C6H14O8S2
Molecular Weight: 278.30
Linear Formula: C6H14O8S2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1252-5MG 5 mg
 $129.00
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45-SML1252-25MG 25 mg
 $509.00
1/EA		 Add To Favorites
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3
InChI key YCPOZVAOBBQLRI-UHFFFAOYSA-N
optical activity [α]/D -4.9 to -5.9°, c = 1 in acetone
Quality Level 100 
SMILES string [S](=O)(=O)(OCC(O)C(O)CO[S](=O)(=O)C)C
solubility H2O: 5 mg/mL, clear
storage temp. −20°C
Biochem/physiol Actions: Alkylating agent, anti-neoplastic agent
Biochem/physiol Actions: Treosulfan is a biofunctional alkylating agent.
Biochem/physiol Actions: Treosulfan is bifunctional alkylating agent.
Biochem/physiol Actions: Treosulfan/l-threitol-1,4-bis-methanesulfonate; dihydroxybusulfan; NSC 39069. It is a prodrug of a bifunctional alkylating cytotoxic agent. Treosulfan can be activated non-enzymatically to two active epoxides. It is used to treat ovarian cancer.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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