Synonym: (2S,3S)-Butanetetraol 1,4-dimesylate; (2S,3S)-Threitol 1,4-bismethanesulfonate; L-Threitol 1,4-bis(methanesulfonate); NSC 39069; Threosulphan; Treosulphan
CAS Number: 299-75-2
Empirical Formula (Hill Notation): C6H14O8S2
Molecular Weight: 278.30
Linear Formula: C6H14O8S2
Product Type: Chemical
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| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3 |
| InChI key |
YCPOZVAOBBQLRI-UHFFFAOYSA-N |
| optical activity |
[α]/D -4.9 to -5.9°, c = 1 in acetone |
| Quality Level |
100  |
| SMILES string |
[S](=O)(=O)(OCC(O)C(O)CO[S](=O)(=O)C)C |
| solubility |
H2O: 5 mg/mL, clear |
| storage temp. |
−20°C |
| Biochem/physiol Actions: |
Alkylating agent, anti-neoplastic agent |
| Biochem/physiol Actions: |
Treosulfan is a biofunctional alkylating agent. |
| Biochem/physiol Actions: |
Treosulfan is bifunctional alkylating agent. |
| Biochem/physiol Actions: |
Treosulfan/l-threitol-1,4-bis-methanesulfonate; dihydroxybusulfan; NSC 39069. It is a prodrug of a bifunctional alkylating cytotoxic agent. Treosulfan can be activated non-enzymatically to two active epoxides. It is used to treat ovarian cancer. |
| Packaging: |
5, 25 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
−20°C |
| UNSPSC |
12352200 |